|There is now considerable evidence
that progressive tumor growth and its metastatic spread
are angiogenesis dependent. The pervasive role of tumor
microenvironment and the intricate communication between
the tumor and its host tissue attracted enormous
scientific attention. The field of tumor angiogenesis has
seen an explosive growth over the last couple of years.
Preclinical as well as early clinical evaluation of novel
compounds is progressing at a rapid pace. The advent of
high throughput technologies (i.e., transcriptomics,
proteomics, epigenomics and functional genomics) has
fueled hopes to systematically uncover the molecular
events underlying cancer development and progression.
In order to tackle the multifaceted nature of tumor biology we have built an international and multidisciplinary consortium consisting of physicians, biologists, biochemists, physicists, mathematicians and computer scientists from the four institutions:
Our research goals are: