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With:
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Emami B, Graham MV, 1997. Lung. In : Principles and Practice of Radiation Oncology, Parez CA & Brady LW, eds, 3rd edition, Philadelphia, pp. 1181-1220. Tolerance of normal tissue to therapeutic radiation. Int. J. Radiat. Oncol. Biol. Phys. 21: 109–122. | |
T. S. KEHWAR, Ph. D., D. Sc. & *S. C. SHARMA, M.D. USE OF NORMAL TISSUE TOLERANCE DOSES INTO LINEAR QUADRATIC EQUATION TO ESTIMATE NORMAL TISSUE COMPLICATION PROBABILITY. http://www.rooj.com/Radiation%20Tissue%20Tolerance.htm | |
SFJRO - eLQ eLQ - Radiation therapy dose calculator - Linear quadratic model SFRA - Societe Francaise de Radiotherapie Oncoloquiqe http://www.sfjro.fr/ilq/en/ |
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with: | ||
D | = total dose [Gy](= n*d) | |
d | = dose per fraction [Gy] | |
n | = number of fractions | |
α/β | = tissue dependent sensitivity factor |
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with: | ||
T | = total treatment time [days] | |
Tk | = kick off time [days], period between radiation start and onset of tumor repopulation | |
Teff | = effective tumor doubling time [days] | |
α | = linear coefficient of Linear quadratic model | |
Fowler at al. 21 years of Biologically Effective Dose. Br J Radiol. 2010 July; 83(991): 554 – 568 |
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with: | ||
RBEmax | = respective RBE Jones et al., The role of biologically effective dose (BED) in clinical oncology, Clinical Oncology, 13(2), 2001, 71-81. |
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